Home to about 8·2% of the global population, Latin America experienced a disproportionate burden of COVID-19. The region reported 80 million COVID-19 cases and 1·7 million deaths, representing 10% and 25% of global figures.1 Latin America accounts for the highest loss of years of life expectancy at birth in 2021 versus 2019.2 There was scarce collaboration...

Journalist Linda Villarosa's writing has scrutinised pervasive racial health inequities in the USA, challenging health professionals and wider society to recognise the adverse impacts of racism on health. Her insights come from in-depth research, but her outlook is also influenced by the racism she experienced in childhood. Following the achievements...

Indigenous Dene Elder Francois Paulette from northern Canada talked about climate change at the 2015 Parliament of the World Regions and warned “Your way of life is killing my way of life.”1 He ended his speech with the words: “Rise! It's time to stand up for our future.”1 More than 8 years after this speech, an estimated 68% of the Northwest Territories,...

GBD 2021 Causes of Death Collaborators. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet 2024; published online April 3. https://doi.org/10.1016/S0140-6736(24)00367-2—In this Article,...

China is home to the second largest population of children and adolescents in the world. Yet demographic shifts mean that the government must manage the challenge of fewer children with the needs of an ageing population, while considering the delicate tension between economic growth and environmental sustainability. We mapped the health problems and...

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease characterised by the presence of autoantibodies towards nuclear antigens, immune complex deposition, and chronic inflammation at classic target organs such as skin, joints, and kidneys. Despite substantial advances in the diagnosis and management of SLE, the burden of disease remains...