Bioinformatics - RSS feed of current issue
535 followers 5 نوشته / هفته
Correction to: Rapid generation of high-quality structure figures for publication with PyMOL-PUB

This is a correction to: Yuting Chen, Haoling Zhang, Wen Wang, Yue Shen, Zhi Ping, Rapid generation of high-quality structure figures for publication with PyMOL-PUB, Bioinformatics, Volume 40, Issue 3, March 2024, btae139, https://doi.org/10.1093/bioinformatics/btae139.

Sat Apr 27, 2024 15:41
GAUSS: a summary-statistics-based R package for accurate estimation of linkage disequilibrium for variants, Gaussian imputation, and TWAS analysis of cosmopolitan cohorts

AbstractMotivationAs the availability of larger and more ethnically diverse reference panels grows, there is an increase in demand for ancestry-informed imputation of genome-wide association studies (GWAS), and other downstream analyses, e.g. fine-mapping. Performing such analyses at the genotype level is computationally challenging and necessitates,...

Sat Apr 27, 2024 15:41
Efficient cytometry analysis with FlowSOM in Python boosts interoperability with other single-cell tools

AbstractMotivationWe describe a new Python implementation of FlowSOM, a clustering method for cytometry data.ResultsThis implementation is faster than the original version in R, better adapted to work with single-cell omics data including integration with current single-cell data structures and includes all the original visualizations, such as the star...

Sat Apr 27, 2024 15:41
Effect of tokenization on transformers for biological sequences

AbstractMotivationDeep-learning models are transforming biological research, including many bioinformatics and comparative genomics algorithms, such as sequence alignments, phylogenetic tree inference, and automatic classification of protein functions. Among these deep-learning algorithms, models for processing natural languages, developed in the natural...

Sat Apr 27, 2024 15:41
VirusPredictor: XGBoost-based software to predict virus-related sequences in human data

AbstractMotivationDiscovering disease causative pathogens, particularly viruses without reference genomes, poses a technical challenge as they are often unidentifiable through sequence alignment. Machine learning prediction of patient high-throughput sequences unmappable to human and pathogen genomes may reveal sequences originating from uncharacterized...

Sat Apr 27, 2024 15:41
Integrative annotation scores of variants for impact on RNA binding protein activities

AbstractMotivationThe ENCODE project generated a large collection of eCLIP-seq RNA binding protein (RBP) profiling data with accompanying RNA-seq transcriptomes of shRNA knockdown of RBPs. These data could have utility in understanding the functional impact of genetic variants, however their potential has not been fully exploited. We implement INCA...

Thu Apr 25, 2024 03:36

خوراک خبری خود را بسازید

آیا آماده هستید تا آن را اجرا کنید؟
بدون نیاز به کارت اعتباری، یک دوره آزمایشی 14 روزه را شروع کنید.

ایجاد حساب‌کاربری