Bioinformatics - current issue
This is a correction to: Yuting Chen, Haoling Zhang, Wen Wang, Yue Shen, Zhi Ping, Rapid generation of high-quality structure figures for publication with PyMOL-PUB, Bioinformatics, Volume 40, Issue 3, March 2024, btae139, https://doi.org/10.1093/bioinformatics/btae139.
AbstractMotivationAs the availability of larger and more ethnically diverse reference panels grows, there is an increase in demand for ancestry-informed imputation of genome-wide association studies (GWAS), and other downstream analyses, e.g. fine-mapping. Performing such analyses at the genotype level is computationally challenging and necessitates,...
AbstractMotivationWe describe a new Python implementation of FlowSOM, a clustering method for cytometry data.ResultsThis implementation is faster than the original version in R, better adapted to work with single-cell omics data including integration with current single-cell data structures and includes all the original visualizations, such as the star...
AbstractMotivationDeep-learning models are transforming biological research, including many bioinformatics and comparative genomics algorithms, such as sequence alignments, phylogenetic tree inference, and automatic classification of protein functions. Among these deep-learning algorithms, models for processing natural languages, developed in the natural...
AbstractMotivationDiscovering disease causative pathogens, particularly viruses without reference genomes, poses a technical challenge as they are often unidentifiable through sequence alignment. Machine learning prediction of patient high-throughput sequences unmappable to human and pathogen genomes may reveal sequences originating from uncharacterized...
AbstractMotivationThe ENCODE project generated a large collection of eCLIP-seq RNA binding protein (RBP) profiling data with accompanying RNA-seq transcriptomes of shRNA knockdown of RBPs. These data could have utility in understanding the functional impact of genetic variants, however their potential has not been fully exploited. We implement INCA...
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