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The effects of low HER2 expression on survival in patients with metastatic breast cancer treated with CDK 4/6 inhibitors: a multicenter retrospective study

ConclusionThe prognostic value of HER2-low status remains controversial. Our study showed no significant effect of HER2 low expression on survival in patients receiving CDK 4/6i plus ET. (Source: Breast Cancer Research and Treatment)

Sat May 18, 2024 23:06
Development of a core set of outcome measures to be applied toward breast cancer-related lymphedema core outcome domains

ConclusionNarrowing the choices of OMs to 27 highly recommended by BCRL experts may reduce selective reporting, inconsistency in clinical use, and variability of reporting across interdisciplinary healthcare fields which manage or research BCRL. There is a need for valid, reliable, and feasible OMs that measure tissue consistency. Measures of upper...

Sat May 18, 2024 23:06
Germline pathogenic variants associated with triple-negative breast cancer in US Hispanic and Guatemalan women using hospital and community-based recruitment strategies

ConclusionGuatemalan and US Hispanic women have rates of hereditary breast cancer pathogenic variants similar to other populations and are more likely to have early age at diagnosis, a family history, and a more aggressive disease. Patient recruitment was higher using hospital-based versus community enrollment. This data supports genetic testing in...

Sat May 18, 2024 23:06
Racial disparities in initiation of chemotherapy among breast cancer patients with discretionary treatment indication in the state of Georgia

ConclusionWe observed racial disparities in the initiation of chemotherapy overall and by sociodemographic and clinical factors, and more equitable outcomes when clinical guidelines were followed. (Source: Breast Cancer Research and Treatment)

Sat May 18, 2024 23:06
Trends in socioeconomic inequalities in breast cancer mortality in Canada: 1992 –2019

ConclusionThe increasing concentration of breast cancer mortality among low socioeconomic status females remains a challenge in Canada. Continuous efforts are needed within Canadian healthcare system  to improve the prevention and treatment of breast cancer for this population. (Source: Breast Cancer Research and Treatment)

Sat May 18, 2024 23:06
Is the CTS5 a helpful decision-making tool in the extended adjuvant therapy setting?

ConclusionThe CTS5 is a reliable prognostic tool that is well calibrated in the lower and intermediate risk groups with a substantial difference of expected versus observed LDR rates in high-risk patients. While a numerical trend in favoring prolonged ET for patients with a higher CTS5 was found, a significantly predictive value for the score could...

Sat May 18, 2024 23:06

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