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Combined transcriptome and proteome analysis reveals MSN and ARFIP2 as biomarkers for trastuzumab resistance of breast cancer

ConclusionOur findings suggest that MSN and ARFIP2 could serve as promising biomarkers for predicting response to Tz, offering valuable insights for future research in the identification of diagnostic and therapeutic targets for BC patients with Tz resistance. (Source: Breast Cancer Research and Treatment)

Fri May 17, 2024 07:12
Alteration of PD-L1 (SP142) status after neoadjuvant chemotherapy and its clinical significance in triple-negative breast cancer

ConclusionPD-L1 (SP142) status changes after NAC, mostly as a positive conversion. As PD-L1 (SP142) status can convey prognostic and predictive information, it needs to be tested before and after NAC. (Source: Breast Cancer Research and Treatment)

Fri May 17, 2024 07:12
Racial differences in familiarity, interest, and use of integrative medicine among patients with breast cancer

ConclusionBlack patients expressed more interest in IM than their White counterparts; there were no racial differences in IM use, except lower acupuncture use among Black patients. A breast program focused on equity should provide access to these services for patients with breast cancer. (Source: Breast Cancer Research and Treatment)

Thu May 16, 2024 03:15
An exploratory clinical trial of preoperative non-invasive localization before breast-conserving surgery using augmented reality technology

ConclusionAR localization is an acceptable alternative to ultrasound-guided skin marking with no significant differences in surgical outcomes. (Source: Breast Cancer Research and Treatment)

Tue May 14, 2024 23:17
Measuring cfDNA integrity as a biomarker for predicting neoadjuvant chemotherapy response in breast cancer patients: a pilot study

ConclusionsEvaluation of cfDNAI 2 weeks after NAC initiation appears to be an early biomarker for tumor pCR and DFS. Measuring Alu fragments of different lengths may replace techniques requiring prior tumor sequencing to measure ctDNA, reducing costs and complexity of cfDNA serial measurements in BC patients undergoing NAC. (Source: Breast Cancer Research...

Tue May 14, 2024 23:17
Predictive analysis of breast cancer response to neoadjuvant chemotherapy through plasma metabolomics

ConclusionThe application of plasma metabolomics, utilizing CE-MS and LC –MS, may serve as a tool for predicting the efficacy of neoadjuvant chemotherapy in breast cancer in the future after all necessary validations have been completed. (Source: Breast Cancer Research and Treatment)

Tue May 14, 2024 23:17

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