by Weihao Zheng, I-Chang Chang, Jason Limberis, Jonathan M. Budzik, Beth Shoshana Zha, Zachary Howard, Lucas Chen, Joel D. Ernst Mycobacterium tuberculosis (Mtb) infects lung myeloid cells, but the specific Mtb-permissive cells and host mechanisms supporting Mtb persistence during chronic infection are incompletely characterized. We report that...

by Somya Aggarwal, Forrest C. Walker, James S. Weagley, Broc T. McCune, Xiaofen Wu, Lawrence A. Schriefer, Heyde Makimaa, Dylan Lawrence, Pratyush Sridhar, Megan T. Baldridge Noroviruses (NoVs) are a leading cause of viral gastroenteritis. Despite global clinical relevance, our understanding of how host factors, such as antiviral cytokines interferons...

by Zhili Yuan, Pengfei Li, Xin Yang, Xiaowei Cai, Luoyu Wu, Feifei Zhao, Weidong Wen, Mingguo Zhou, Yiping Hou Fusarium head blight (FHB), caused by Fusarium graminearum species complexes (FGSG), is an epidemic disease in wheat and poses a serious threat to wheat production and security worldwide. Profilins are a class of actin-binding proteins...

by Bowei Jiang, Yi Lai, Wenhao Xiao, Tianyu Zhong, Fengping Liu, Junjie Gong, Junyun Huang With the escalating global antimicrobial resistance crisis, there is an urgent need for innovative strategies against drug-resistant microbes. Accumulating evidence indicates microbial extracellular vesicles (EVs) contribute to antimicrobial resistance. Therefore,...

by Domitille Callon, Marie Glenet, Anne-Laure Lebreil, Laetitia Heng, Nicole Bouland, Caroline Fichel, Paul Fornes, Laurent Andreoletti, Fatma Berri Major 5’-terminally deleted (5’TD) RNA forms of group-B coxsackievirus (CVB-5’TD) has been associated with myocarditis in both mice and humans. Although it is known that interferon-β (IFN-β) signaling...

by Etthel M. Windels, Eddie M. Wampande, Moses L. Joloba, W. Henry Boom, Galo A. Goig, Helen Cox, Jerry Hella, Sonia Borrell, Sebastien Gagneux, Daniela Brites, Tanja Stadler Persons living with HIV are known to be at increased risk of developing tuberculosis (TB) disease upon infection with Mycobacterium tuberculosis (Mtb). However, it has remained...